Earnings reviews · 21 slides

Not investment advice; no rating or price target.

Tempus AI Q3 2026 earnings review


Quarter ended September 30, 2026

For information only, not investment advice. No rating or price target.

1 · Cover · Open this slide in DeepCell

Q3 revenue rose 23.1% to $411.5M, beating the LSEG consensus, and adjusted EBITDA turned clearly positive


  1. 1.Non-GAAP EPS of $0.07 beat the LSEG consensus of -$0.08
  2. 2.Data and applications revenue rose 32.9% to $108.1M
  3. 3.Oncology test volume rose 31.8%, while hereditary volume rose 2.1%
  4. 4.Adjusted EBITDA rose to $25.6M from $1.5M
  5. 5.The 2026 revenue guidance low end rose $5.0M to $1,600M
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2 · Key takeaways · Open this slide in DeepCell

Q3 non-GAAP EPS beat the LSEG consensus by $0.15, and revenue beat it by 0.5%


Q3 2026 results vs consensus

MetricActualConsensusVarianceResult
Non-GAAP EPS, LSEG$0.07-$0.08+$0.15Beat
Total net revenue, LSEG$411.5M$409.4M+$2.2M / +0.5%Beat
Non-GAAP EPS, Zacks cross-check$0.07-$0.09+$0.16Beat
Total net revenue, Zacks cross-check$411.5M$411.3M+$0.2M / +0.1%In line

Share price reaction

Not shown: the Nov 2 regular-session close was not confirmed by two sources when this deck was built.

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3 · Q3 versus consensus · Open this slide in DeepCell

Tempus raised the low end of 2026 revenue guidance by $5.0M, in line with consensus at the midpoint


2026 guidance vs consensus

MetricGuidanceConsensusVariancevs Street
Full-year revenue (midpoint), Zacks$1,602.5M$1,600.0M+$2.5M / +0.2%In line
Implied Q4 revenue (midpoint), Zacks$460.4M$455.2M+$5.2M / +1.1%Above

Full-year 2026 guidance, Nov 2 vs Jul 30

MetricJul 30 guidanceNov 2 guidanceChange
Revenue, low end$1,595.0M$1,600.0M+$5.0M
Revenue, high end$1,605.0M$1,605.0M$0.0M
Revenue, midpoint$1,600.0M$1,602.5M+$2.5M
Adjusted EBITDA, about$65.0M$65.0M$0.0M
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4 · Guidance · Open this slide in DeepCell

Total net revenue rose 23.1% and the net loss narrowed to $14.9M from $80.0M


  1. Both segments grewDiagnostics revenue rose 20.0%; data and applications rose 32.9%.
  2. Gross margin widenedGross margin rose to 64.8% from 62.8%.
  3. A one-off gain helpedOther income, net, was $47.1M, mostly fair value gains on securities.

Key figures in $M and YoY % for Q3 2026 vs Q3 2025

$M unless notedQ3 2025Q3 2026YoY
Total net revenue$334.2M$411.5M23.1%
Gross profit$209.9M$266.7M27.0%
Loss from operations($61.0M)($56.9M)n.m.
Adjusted EBITDA$1.5M$25.6Mn.m.
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5 · Q3 at a glance · Open this slide in DeepCell

Data and applications revenue rose 32.9%, faster than diagnostics at 20.0%


Revenue and gross profit by segment

$M unless noted, Q3 2025 vs Q3 2026

SegmentQ3 2025Q3 2026YoYQ3 2026 margin
Diagnostics$252.9M$303.5M20.0%62.4%
Data and applications$81.3M$108.1M32.9%71.5%
Total$334.2M$411.5M23.1%64.8%
Data and applications rose to 26.3% of revenue from 24.3%
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6 · Segment overview · Open this slide in DeepCell

7 · Revenue bridge · Open this slide in DeepCell

Oncology test volume rose 31.8%, while hereditary volume rose only 2.1%


Test volume growth by type

% change YoY in tests, Q3 2026

Oncology tests rose to about 101,500 from 77,000
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8 · Test volume · Open this slide in DeepCell

9 · Gross profit bridge · Open this slide in DeepCell

Gross margin rose 199 bps to 64.8%, led by data and applications


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10 · Margins · Open this slide in DeepCell

Cash used in operations fell to $71.6M in the first nine months from $181.3M


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11 · Cash flow · Open this slide in DeepCell

Remaining performance obligations total $514.0M, with 44% due within a year


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12 · Contracted revenue · Open this slide in DeepCell

Convertible senior notes rose to $1,174.9M as Tempus repaid its term loan and revolver


Cash, debt and equity

$M, Dec 31, 2025 vs Sep 30, 2026

$MDec 31, 2025Sep 30, 2026
Cash and marketable securities$759.7M$854.4M
Total debt$1,239.5M$1,350.8M
Total stockholders’ equity$491.3M$500.4M
Net debt$479.8M$496.5M
Term loan and revolver balances fell to zero from $202.8M and $100.0M
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13 · Balance sheet · Open this slide in DeepCell

Q4 estimates depend on hereditary growth of 2.1% and on SG&A, up 23.4%


Indicator
What to watch
Implication
Q3 reading
Hereditary volume
Growth stays slow
Diagnostics estimates could fall
Hereditary tests rose 2.1%
SG&A
Costs grow faster than revenue
Profit estimates could fall
SG&A rose 23.4%
Fair value gains
Securities gains reverse
Net loss could widen
Other income, net, was $47.1M
Personalis deal
The deal closes after a Nov 30 vote
Guidance could change
Acquisition expenses were $3.7M
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14 · Risks to estimates · Open this slide in DeepCell

15 · Supporting analysis (1/4) · Open this slide in DeepCell

Appendix: supporting analysis for profit and margins


ClaimEvidenceCalculation
Non-GAAP operating income turned positive($8.7M) to $14.4MRelease reconciliation
Stock-based compensation rose$34.0M to $48.1M (41.5%)Release reconciliation
Fair value changes added a gain($41.5M) in Q3 2026, removed from non-GAAP resultsRelease reconciliation
Adjusted EBITDA margin widened0.4% in Q3 2025 and 6.2% in Q3 2026Adjusted EBITDA divided by revenue
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16 · Supporting analysis (2/4) · Open this slide in DeepCell

Appendix: guidance, cash flow and balance sheet support


ClaimEvidenceCalculation
Nine-month revenue$1,142.1M in Jan–Sep 2026, up 26.3%As stated in the release
Implied Q4 adjusted EBITDA$34.2M, the full-year figure less $30.8M to dateGuidance less nine months
Notes refinanced bank debtConvertible notes raised $443.1M; term loan repaid $207.7M; revolver repaid $100.0MNine-month cash flow statement
Receivables roseAccounts receivable $311.2M to $380.7MBalance sheet
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17 · Supporting analysis (3/4) · Open this slide in DeepCell

Appendix: watch items behind guidance and risks


ClaimEvidenceCalculation
SG&A rose$187.9M to $231.9M (23.4%)Statement of operations
Technology R&D rose$38.1M to $45.7M (20.0%)Statement of operations
Interest expense fell$15.4M to $6.7M after the term loan was repaidStatement of operations
Share count roseWeighted-average shares 181.3 million (3.6%)Statement of operations
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18 · Supporting analysis (4/4) · Open this slide in DeepCell

Appendix: operating expense and volume detail


Operating expense detail, $M and YoY %

$M unless notedQ3 2025Q3 2026YoY
Cost of revenues, diagnostics$98.6M$114.0M15.6%
Technology R&D$38.1M$45.7M20.0%
Research and development$45.0M$46.0M2.3%
SG&A$187.9M$231.9M23.4%

Approximate test volume and YoY %

TestsQ3 2025Q3 2026YoY
Oncology77,000101,50031.8%
Hereditary140,000143,0002.1%
Total217,000244,50012.7%
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19 · Appendix: financial detail · Open this slide in DeepCell

Appendix: sources


  • Filing: Tempus AI Form 8-K, Nov 2, 2026 — https://www.sec.gov/Archives/edgar/data/1717115/000119312526442619/tem-ex99_1.htm
  • Filing: Tempus AI Form 10-Q, Nov 2, 2026 — https://www.sec.gov/Archives/edgar/data/1717115/000119312526442624/tem-20260930.htm
  • Prior guidance: Tempus AI Form 8-K, Jul 30, 2026 — https://www.sec.gov/Archives/edgar/data/1717115/000119312526326083/tem-ex99_1.htm
  • Consensus (Q3 results): LSEG data compiled by Reuters, via Boursorama, Nov 2 — https://www.boursorama.com/bourse/actualites/tempus-ai-en-hausse-apres-avoir-annonce-un-benefice-trimestriel-inattendu-002a6d680a8c876a009456656abde658
  • Consensus (cross-check, Q4, full year): Zacks via Yahoo Finance, Nov 2 — https://finance.yahoo.com/markets/stocks/articles/tempus-ai-tem-beats-q3-152003134.html
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20 · Sources · Open this slide in DeepCell

Important disclosures and disclaimer


For information only. This presentation is provided for information only. It is not investment, legal, tax or accounting advice, and it is not an offer, or a solicitation of an offer, to buy or sell any security.

No recommendation. It carries no rating, price target or buy, sell or hold view, and it was prepared without regard to any reader's investment objectives, financial situation or needs.

Sources and accuracy. Company figures come from Tempus AI's Form 8-K (Exhibit 99.1) of November 2, 2026, its Form 10-Q for the quarter ended September 30, 2026, and its Form 8-K of July 30, 2026 for prior guidance. Consensus estimates (LSEG via Reuters and Boursorama, Zacks via Yahoo Finance and AP) are third-party data, credited on the sources page. We have not independently verified third-party data and make no warranty that any information here is accurate, complete or timely.

Forward-looking statements. Company guidance, consensus estimates, remaining performance obligations and the watch items in this deck are forward-looking. They rest on assumptions that may prove wrong, and actual results may differ materially.

Past performance. Past results, including those for Q3 2026, are not a reliable indicator of future results.

Non-GAAP measures. Non-GAAP and adjusted figures follow Tempus AI's own definitions, which exclude items such as stock-based compensation and fair value changes. They supplement, and do not replace, GAAP results, and they may not be comparable with other companies' measures. The earnings release reconciles them to GAAP.

No liability. No liability is accepted for any direct or indirect loss arising from the use of this presentation or its contents.

No affiliation. This presentation is not affiliated with, reviewed or endorsed by Tempus AI, Inc. and does not represent its views. Company names belong to their owners.

How it was made. The deck was built with DeepCell, with figures linked to a model in the file. Readers should check the figures against the original filings and consult a qualified professional adviser before making any investment decision.

Date of analysis. The analysis reflects information available as of November 2, 2026. It will not be updated for later events, and views may change without notice.

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21 · Important disclosures · Open this slide in DeepCell